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Of mice and men
Super treat in the lab this week. The journal Science decided to feature one of our publications in its “Editor’s Choice” section. The author of the little piece is Laura Zahn and she chose to feature the work, which was published in Molecular Biology and Evolution. It is always a real thrill to have work…
Cover of Structure (Cell Press)
In a recent collaboration with Joe Cockburn et al published in Structure – we reveal the structure of the cargo binding TPR domain of kinesin light chain bound to the cargo molecule JIP3. Along with solving the crystal structure – the biophysical and evolutionary analysis we carried out have revealed the kinesin-1 cargo binding site…
Paternally Expressed Imprinted Genes under Positive Darwinian Selection in Arabidopsis thaliana.
In this paper in MBE we examined the selective pressure variation across genomically imprinted genes in the inbreeding species Arabidopsis thaliana. Genomic imprinting is an epigenetic phenomenon where autosomal genes display uniparental expression depending on whether they are maternally or paternally inherited. Genomic imprinting can arise from parental conflicts over resource allocation to the offspring, which…
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Placental Mammals and the limits of phylogenetic inference
More support for Atlantogenata. This week an international collaborative effort has tackled a major challenge in phylogenetics – the interrelationships amongst placental mammals. The paper has just been published in Genome Biology and Evolution (please click here to see the paper). In work led by Dr James Tarver and Dr Davide Pisani (with contributions from…
Postdoc Positions Available
I am looking for two highly motivated computational evolutionary biologists with excellent programming and computing skills to join my team at the University of Nottingham. Both positions are fully funded for two years with an option to extend pending grant success. Both positions are computational in nature and require strong programming, molecular evolution and genome…