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This is the administrative account for the Computational & Molecular Evolutionary Biology Group at the University of Nottingham. Please browse through our site and contact us if you have any questions.
Inadvertent Paralog Inclusion Drives Artifactual Topologies and Timetree Estimates in Phylogenomics
In work lead by Dr Karen Siu Ting she addresses an important question in phylogenomics using 18 amphibian species. She chose to work on this Lissamphibian group because there is significant conflict over their relationships to one another, and because transcriptomes are increasingly being used to overcome the lack of genomic data for this clade.…
Return to the sea, get huge, beat cancer: an analysis of cetacean genomes including an assembly for the humpback whale…
In the May issue of MBE we have published the outcome of a collaboration with Dr Marc Tollis, Prof Carlo Maley, Prof Per Palsbol and others where we sequenced and analysed the genome of the humpback whale. The paper aimed to Peto’s Paradox – where large-bodied and long-lived animals do not suffer higher risks of…
Paternally Expressed Imprinted Genes under Positive Darwinian Selection in Arabidopsis thaliana.
In this paper in MBE we examined the selective pressure variation across genomically imprinted genes in the inbreeding species Arabidopsis thaliana. Genomic imprinting is an epigenetic phenomenon where autosomal genes display uniparental expression depending on whether they are maternally or paternally inherited. Genomic imprinting can arise from parental conflicts over resource allocation to the offspring, which…
Cover of Structure (Cell Press)
In a recent collaboration with Joe Cockburn et al published in Structure – we reveal the structure of the cargo binding TPR domain of kinesin light chain bound to the cargo molecule JIP3. Along with solving the crystal structure – the biophysical and evolutionary analysis we carried out have revealed the kinesin-1 cargo binding site…
New York Furniture Expo
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2017-2018 USA Wine events
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Modern Lifestyle
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